
Before the release of draft EPA Method 1633 in 2021, there were few standardized methods for PFAS in nonpotable water. ISO 21675 was published in 2019 to cover a list of 30 PFAS compounds in drinking, natural and waste water containing less than 2 g/L of solids1. The main challenge of extracting samples with particulates is SPE cartridge clogging, which requires additional steps of dividing a sample between cartridges and pooling the extracts.
This application note presents a streamlined extraction of non-potable water samples using PromoChrom’s high-capacity inline filters along with the automated SPE-03 system for the 30 compounds of ISO 21675, as well as 3 additional pertinent PFAS compounds.

